Biotin was originally called vitamin H, belonging to the successors of water-soluble B vitamins. Biotin is composed by the imidazole round and a tetrahydrocannabinol with valerate It is the thiophene sulfur monocarboxylate Nutritionists hold prevalent and in-depth study in functions of biotin.
Production applications and special features of biotin
Glucokinase is a clue enzyme regulating liver glucose intake. The scarcity of biotin in mice glucose tolerance assessment curve, hepatic glucose phosphorylation and glycogen storage was significantly higher than non-deficient mice, which is caused by liver glucokinase assignment Sufficient quantities and pharmacological doses of biotin in the diet of liver glucokinase activity and is not limited to biotin-deficient mice, diabetic mice and in vitro cultured mouse liver cells are equally effective. Using molecular biology techniques can prove that the stimulus originate of biotin occurs at the transcriptional level
Biotin as a coenzyme of the carboxylase, can also moderate gene expression, such as incubation and immune procedure processes in the entity plays a broader role. The biotin regulates the duration of key genes of intermediary metabolism that role and biological factors involved in the preservation of body glucose and lipid homeostasis role of. Biotin dearth and to reduce glucose tolerance and glucose utilization Excess of biotin can revise diabetes grade Supplementary biotin reduced the postprandial glucose concentration in patients with hereditary diabetic mice and induced non-insulin-dependent diabetic mice improved their glucose tolerance.
Pharmacological doses of biotin can impair blood lipid levels The cosmetic green material suppliersexperiments declare that clean volunteers lipid concentration decreased after verbal administration of biotin Atherosclerosis and hyperlipidemia patients daily doses of 5 mg of biotin, the decrease of hypercholesterolemia after 4 weeks Biotin in the role of the carbohydrate metabolism and its pharmacological doses of non-toxic, showing biotin for the treatment of hyperglycemia and hyperlipidemia, corpulence prevention and more aspects entrust have goodly application prospects.
Animal physiology, animal biochemistry, immunology and fresh disciplines, kinsfolk continue to locate the biological function of the nutrients In elapsed decades the study of biotin, biotin plays an famous role in immune function, and boost the knot of unsusceptible organs Early tests showed that biotin deficiency, combined with 32P into RNA and DNA was inhibited, resulting in the DNA subject of the spleen cell break capacity and organ reject in cell proliferation was inhibited
Biotin can rectify animal action in moulding It is also used in the treatment of human diabetes. To date, research on mobility gadget of biotin is already underway As people gradually obtain deep harmony of the biotin, biotin as an indispensable additive in animal nutrition, the increasing roles entrust gradually be revealed It can be predicted that biotin has a broader application in the forming of animal, human health care and abrasion care.Source:http://wwwcosprmcom